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Mixtral 8x7B Instruct on NVIDIA GeForce RTX 4090

NVIDIA GeForce RTX 4090 handles Mixtral 8x7B Instruct well at 35 tok/s at Q3_K_M. A solid choice for this model.

Model Size

46.7B

Device VRAM

24 GB

Bandwidth

1008 GB/s

Quantizations Tested

1

Performance by Quantization

Each row shows Mixtral 8x7B Instruct performance at a different quality level on NVIDIA GeForce RTX 4090.

QuantizationSpeedTTFTFits in VRAMRatingConfidence
Q3_K_M35 tok/s300ms✓ YesGoodestimated

Notes

Q3_K_M

Q3 at 21GB fits on 24GB VRAM with 3GB headroom. MoE sparsity means speed is good despite quantization level. For Q4 quality, need 36GB+ VRAM (M4 Max).

About Mixtral 8x7B Instruct

Mixtral 8x7B Instruct (46.7B) is a chat, coding, reasoning, multi-purpose model. Mixture of Experts model — 46.7B total params but only ~12.9B active per token. Excellent quality-to-speed ratio. Despite large total params, inference speed closer to a 13B model. Needs more VRAM for the full weight set though.

View all Mixtral 8x7B Instruct hardware options →

About NVIDIA GeForce RTX 4090

NVIDIA GeForce RTX 4090 has 24 GB at 1008 GB/s. Street price: $1,799.

See all models NVIDIA GeForce RTX 4090 can run →

Builds with NVIDIA GeForce RTX 4090

Source: MoE model benchmarks (2026-01-15)

Data last updated: 2026-03-01