MistralMistral
Compatibility Report

Mixtral 8x7B Instruct on NVIDIA RTX PRO 6000 Blackwell

Yes — RTX PRO 6000 Blackwell runs Mixtral 8x7B Instruct excellently at Q5_K_M — 125 tok/s. 96 GB VRAM with plenty of headroom.

Model Size

46.7B

Device VRAM

96 GB

Bandwidth

1800 GB/s

Quantization

Q5_K_M

Benchmarks

Performance by Quantization

OwnRig currently has one published compatibility entry for Mixtral 8x7B Instruct on NVIDIA RTX PRO 6000 Blackwell at Q5_K_M. This is the best supported pairing we can stand behind today.

QuantizationSpeedTTFTFits in VRAMRatingConfidence
Q5_K_M125 tok/s40ms✓ YesExcellentestimated

Notes

Q5_K_M

96 GB GDDR7 fits Q5_K_M (31.4 GB) with 65 GB headroom. 1.8 TB/s bandwidth. High quality quantization with good speed.

About Mixtral 8x7B Instruct

Mixtral 8x7B Instruct (46.7B) is a chat, coding, reasoning, multi-purpose model. Mixture-of-Experts model: 46.7B total params but only ~12.9B active per token. Quality closer to a 13B dense model with inference speed to match. Needs more VRAM for the full weight set though.

View all Mixtral 8x7B Instruct hardware options →

About NVIDIA RTX PRO 6000 Blackwell

NVIDIA RTX PRO 6000 Blackwell has 96 GB at 1800 GB/s. Street price: $7,500.

See all models NVIDIA RTX PRO 6000 Blackwell can run →

Estimate method: Estimated from bandwidth ratio vs RTX 4090 (1800/1008 = 1.78x) with conservative margin. Reference hardware source: nvidia.com (2026-03-29)

Performance varies by driver version, inference engine, quantization method, context length, and system configuration. Figures shown are estimates based on community benchmarks and may not reflect your exact setup. Product names are trademarks of their respective owners. OwnRig is independent and not affiliated with any hardware or AI model provider.