QwenQwen
Compatibility Report

Qwen 2.5 72B Instruct on Apple M4 Ultra (192GB)

M4 Ultra (192GB) runs Qwen 2.5 72B Instruct at Q4_K_M — 9 tok/s. Usable on 192 GB VRAM — see full quantization options below.

Model Size

72.7B

Device VRAM

192 GB

Bandwidth

819 GB/s

Quantization

Q4_K_M

Benchmarks

Performance by Quantization

OwnRig currently has one published compatibility entry for Qwen 2.5 72B Instruct on Apple M4 Ultra (192GB) at Q4_K_M. This is the best supported pairing we can stand behind today.

QuantizationSpeedTTFTFits in VRAMRatingConfidence
Q4_K_M9 tok/s1467ms✓ YesAcceptableestimated

Notes

Q4_K_M

M4 Ultra: ~1.5x M4 Max performance due to higher memory bandwidth and GPU cores.

About Qwen 2.5 72B Instruct

Qwen 2.5 72B Instruct (72.7B) is a chat, coding, ai coding, reasoning, multi-purpose model. Top-tier 72B model, competitive with Llama 3.1 70B. Capable at coding and structured output. Requires 48 GB+ VRAM for usable quantizations.

View all Qwen 2.5 72B Instruct hardware options →

About Apple M4 Ultra (192GB)

Apple M4 Ultra (192GB) has 192 GB at 819 GB/s. Available in Mac Studio, Mac Pro.

See all models Apple M4 Ultra (192GB) can run →

Estimate method: Estimated from M4 Max benchmarks scaled by memory bandwidth ratio (819/546 GB/s). Reference hardware source: github.com (2026-03-14)

Performance varies by driver version, inference engine, quantization method, context length, and system configuration. Figures shown are estimates based on community benchmarks and may not reflect your exact setup. Product names are trademarks of their respective owners. OwnRig is independent and not affiliated with any hardware or AI model provider.