QwenQwen 2.5 72B Instruct on AMD Radeon Pro W7900
AMD Radeon Pro W7900 runs Qwen 2.5 72B Instruct at Q3_K_M — 6 tok/s. Usable on 48 GB VRAM — see full quantization options below.
Model Size
72.7B
Device VRAM
48 GB
Bandwidth
864 GB/s
Quantization
Q3_K_M
Performance by Quantization
OwnRig currently has one published compatibility entry for Qwen 2.5 72B Instruct on AMD Radeon Pro W7900 at Q3_K_M. This is the best supported pairing we can stand behind today.
| Quantization | Speed | TTFT | Fits in VRAM | Rating | Confidence |
|---|---|---|---|---|---|
| Q3_K_M | 6 tok/s | 1852ms | ✓ Yes | Acceptable | estimated |
Notes
Q3_K_M
AMD workstation card with the best ROCm support in this dataset; best AMD option for larger models. Q3_K_M fits in VRAM on this card.
About Qwen 2.5 72B Instruct
Qwen 2.5 72B Instruct (72.7B) is a chat, coding, ai coding, reasoning, multi-purpose model. Top-tier 72B model, competitive with Llama 3.1 70B. Capable at coding and structured output. Requires 48 GB+ VRAM for usable quantizations.
View all Qwen 2.5 72B Instruct hardware options →About AMD Radeon Pro W7900
AMD Radeon Pro W7900 has 48 GB at 864 GB/s. Street price: $3,299.
See all models AMD Radeon Pro W7900 can run →Estimate method: Estimated from m4-max-64gb compatibility patterns plus ROCm/Vulkan adjustments. Reference hardware source: github.com (2026-03-26)
Performance varies by driver version, inference engine, quantization method, context length, and system configuration. Figures shown are estimates based on community benchmarks and may not reflect your exact setup. Product names are trademarks of their respective owners. OwnRig is independent and not affiliated with any hardware or AI model provider.