Qwen 2.5 72B Instruct on NVIDIA GeForce RTX 4060 8GB
NVIDIA GeForce RTX 4060 8GB cannot run Qwen 2.5 72B Instruct at any quantization level. The 8 GB of VRAM is insufficient.
Model Size
72.7B
Device VRAM
8 GB
Bandwidth
272 GB/s
Quantizations Tested
1
Performance by Quantization
Each row shows Qwen 2.5 72B Instruct performance at a different quality level on NVIDIA GeForce RTX 4060 8GB.
| Quantization | Speed | TTFT | Fits in VRAM | Rating | Confidence |
|---|---|---|---|---|---|
| Q2_K | — | — | ✗ Offload | Not Viable | estimated |
Notes
Q2_K
72B class. Not viable on 8GB.
About Qwen 2.5 72B Instruct
Qwen 2.5 72B Instruct (72.7B) is a chat, coding, ai coding, reasoning, multi-purpose model. Top-tier 72B model, competitive with Llama 3.1 70B. Excellent at coding and structured output. Requires 48GB+ VRAM for usable quantizations.
View all Qwen 2.5 72B Instruct hardware options →About NVIDIA GeForce RTX 4060 8GB
NVIDIA GeForce RTX 4060 8GB has 8 GB at 272 GB/s. Street price: $289.
See all models NVIDIA GeForce RTX 4060 8GB can run →Source: 72B model exceeds 8GB (2026-03-15)
Data last updated: 2026-03-01