QwenQwen
Compatibility Report

Qwen 2.5 72B Instruct on NVIDIA GeForce RTX 4060 8GB

RTX 4060 8GB cannot run Qwen 2.5 72B Instruct. 8 GB VRAM is insufficient at any quantization level.

Model Size

72.7B

Device VRAM

8 GB

Bandwidth

272 GB/s

Quantization

Q2_K

Benchmarks

Performance by Quantization

OwnRig currently has one published compatibility entry for Qwen 2.5 72B Instruct on NVIDIA GeForce RTX 4060 8GB at Q2_K. This pairing has limitations β€” check the rating and notes below.

QuantizationSpeedTTFTFits in VRAMRatingConfidence
Q2_Kβ€“β€“βœ— OffloadNot viableestimated

Notes

Q2_K

72B class. Not viable on 8GB.

About Qwen 2.5 72B Instruct

Qwen 2.5 72B Instruct (72.7B) is a chat, coding, ai coding, reasoning, multi-purpose model. Top-tier 72B model, competitive with Llama 3.1 70B. Capable at coding and structured output. Requires 48 GB+ VRAM for usable quantizations.

View all Qwen 2.5 72B Instruct hardware options β†’

About NVIDIA GeForce RTX 4060 8GB

NVIDIA GeForce RTX 4060 8GB has 8 GB at 272 GB/s. Street price: $289.

See all models NVIDIA GeForce RTX 4060 8GB can run β†’

Estimate method: 72B model exceeds 8GB. Reference hardware source: github.com (2026-03-15)

Performance varies by driver version, inference engine, quantization method, context length, and system configuration. Figures shown are estimates based on community benchmarks and may not reflect your exact setup. Product names are trademarks of their respective owners. OwnRig is independent and not affiliated with any hardware or AI model provider.