
Qwen 2.5 72B Instruct on AMD Radeon RX 7600
AMD Radeon RX 7600 cannot run Qwen 2.5 72B Instruct. 8 GB VRAM is insufficient at any quantization level.
Model Size
72.7B
Device VRAM
8 GB
Bandwidth
288 GB/s
Quantization
Q2_K
Performance by Quantization
OwnRig currently has one published compatibility entry for Qwen 2.5 72B Instruct on AMD Radeon RX 7600 at Q2_K. This pairing has limitations β check the rating and notes below.
| Quantization | Speed | TTFT | Fits in VRAM | Rating | Confidence |
|---|---|---|---|---|---|
| Q2_K | β | β | β Offload | Not viable | estimated |
Notes
Q2_K
Budget RDNA 3 card. Vulkan is the most reliable local runtime; ROCm support is more limited. Q2_K needs ~25.3GB and relies on offloading on this card.
About Qwen 2.5 72B Instruct
Qwen 2.5 72B Instruct (72.7B) is a chat, coding, ai coding, reasoning, multi-purpose model. Top-tier 72B model, competitive with Llama 3.1 70B. Capable at coding and structured output. Requires 48 GB+ VRAM for usable quantizations.
View all Qwen 2.5 72B Instruct hardware options βAbout AMD Radeon RX 7600
AMD Radeon RX 7600 has 8 GB at 288 GB/s. Street price: $239.
See all models AMD Radeon RX 7600 can run βEstimate method: Estimated from rtx-4060-8gb compatibility patterns plus ROCm/Vulkan adjustments. Reference hardware source: github.com (2026-03-26)
Performance varies by driver version, inference engine, quantization method, context length, and system configuration. Figures shown are estimates based on community benchmarks and may not reflect your exact setup. Product names are trademarks of their respective owners. OwnRig is independent and not affiliated with any hardware or AI model provider.