QwenQwen 2.5 72B Instruct on AMD Radeon RX 7900 XTX
AMD Radeon RX 7900 XTX cannot run Qwen 2.5 72B Instruct. 24 GB VRAM is insufficient at any quantization level.
Model Size
72.7B
Device VRAM
24 GB
Bandwidth
960 GB/s
Quantization
Q2_K
Performance by Quantization
OwnRig currently has one published compatibility entry for Qwen 2.5 72B Instruct on AMD Radeon RX 7900 XTX at Q2_K. This pairing has limitations — check the rating and notes below.
| Quantization | Speed | TTFT | Fits in VRAM | Rating | Confidence |
|---|---|---|---|---|---|
| Q2_K | 2 tok/s | 5815ms | ✗ Offload | Marginal | estimated |
Notes
Q2_K
ROCm can run large models well on RDNA 3, though CUDA equivalents still have broader tooling support. Q2_K needs ~25.3GB and relies on offloading on this card.
About Qwen 2.5 72B Instruct
Qwen 2.5 72B Instruct (72.7B) is a chat, coding, ai coding, reasoning, multi-purpose model. Top-tier 72B model, competitive with Llama 3.1 70B. Capable at coding and structured output. Requires 48 GB+ VRAM for usable quantizations.
View all Qwen 2.5 72B Instruct hardware options →About AMD Radeon RX 7900 XTX
AMD Radeon RX 7900 XTX has 24 GB at 960 GB/s. Street price: $849.
See all models AMD Radeon RX 7900 XTX can run →Builds with AMD Radeon RX 7900 XTX
Estimate method: Estimated from m4-max-64gb compatibility patterns plus ROCm/Vulkan adjustments. Reference hardware source: github.com (2026-03-26)
Performance varies by driver version, inference engine, quantization method, context length, and system configuration. Figures shown are estimates based on community benchmarks and may not reflect your exact setup. Product names are trademarks of their respective owners. OwnRig is independent and not affiliated with any hardware or AI model provider.